BIMM-SOL project (2016-2018)

The goal of this project is to commercialize processes for analyzing molecular microbial biomarkers in the qualitative biological diagnosis of soils.

About the project: https://librairie.ademe.fr/recherche-et-innovation/2272-bimm-sol.html

Funding:

logo ADEME

DIAMA project (2016-2021)

The DIAMA project is assessing and validating the Deeplex® Myc-TB test in Africa and Europe. This rapid molecular test (based on mass sequencing) detects and genotypes mycobacteria and predicts antituberculosis drug resistance in Mycobacterium tuberculosis complex strains.

Partners:

Funding:

logo Horizon Europe

FLU-MICROBIOT project (2015-2018)

The goal of this project is to understand the role of microbiotas and the gastrointestinal and respiratory tracts in influenza co-infections.

Partners:

Funding:

logo bpi france rond 

BioDISSPOL project (2015-2018)

Development of microbial biomarkers for the identification and monitoring of sites polluted by chlorinated solvents.

Partners:

Funding:

logo ADEME 

MICROTYPE project (2014-2018)

This project underpins the worldwide surveillance of infectious agents like Brucella (the bacterium responsible for brucellosis) via the development of typing kits and databases.

Partners:

Funding:

logo agence nationale de la recherche ANR
 

Our turnkey solutions to exploit the potential of metagenomics

You are looking for:

  • Outsource your DNA and/or RNA extractions and benefit from our optimized and standardized protocols.
  • Determine the bacterial, eukaryote and/or fungal biomass in extracted gDNA.
  • Define and characterize the biodiversity of the microbial communities in your samples.
  • Access to the functional potential of microbial communities of interest.
  • Describe and study the microbial communities’ active functions.
  • Detect and quantify specific bacteria of interest and measure changes in their abundance.
en travaillant avec genoscreen

Discover our turnkey solutions:

DNA & RNA extraction

Benefit from our optimized, standardized and reproductible protocols for all types of initial matrix (including negative and positive controls).

 

Microbial biomass

Estimate the quantity of gDNA corresponding to the microbial community in your samples, by using complex standard curves that are appropriate for your field of interest (intestinal, cutaneous microbiota etc.).

 

Metabiote®

Use a standardized approach for the targeted analysis of ubiquitous genes (16S rRNA, ITS 1/2, 18S rRNA, etc.), in order to:

  • characterize microbial communities and their biodiversity,
  • observe changes in the abundance of taxa of interest.
 

Shotgun metagenomics

Get an overview of the organisms present in your samples such as:

  • identification down to species
  • calculation of relative abundances and diversity indices
  • functional analyses

 

Metatranscriptomics

Characterize changes in gene expression within microbial communities, in order to better understand their main functions and how they adapt to their environment.

 

Bacterial counts

Determine or validate changes in the abundance of specific bacteria using qPCR. Ask for a feasability study on your specific target or benefit from our «ready-to-qPCR» assays.

 

 

About us

GenoScreen is a French biotech company specialised in genomics and bioinformatics. We offer innovative services and solutions based on the characterization and exploitation of DNA/RNA molecules.

GenoScreen works on all kinds of genomes (Human, animal, plant and microbial) and delivers solutions for research groups from the private and public sectors.

Our microbial expertise continues to deepen since 2008, alongside the development of optimized and standardized, analytical protocols by our R&D team.

As the French leader in this sector, GenoScreen offers solutions that address your needs to characterize and understand microbiota.

Work with GenoScreen and benefit from:

  • Cutting-edge service provision since 2001
  • Personalized interaction with highly qualified staff
  • Dedicated solutions to suit your needs
  • A unique and reliable partner
en travaillant avec genoscreen

They used our services:

Custom qPCR service

GenoScreen supports you in developing and optimizing your custom qPCR tests. Our team designs specific assays tailored to your need, whether for detecting genetically modified strains, differentiating species at the desired taxonomic level (strain, species, genus), or analyzing genes of interest (enzymatic function, RT-qPCR, etc.).

 

Advanced expertise in custom qPCR

Introduction
Custom qPCR development

In silico design, in vitro validation, and optimization of experimental conditions.

Optimization and validation of existing designs

Improved sensitivity, efficiency, and robustness.

Method transfer and equipment validation

Support for implementing the method on your own platforms.

Comprehensive analytical performance evaluation

Determination of LOD (limit of detection) and LOQ (limit of quantification), testing on complex matrices.

Our workflow applied to qPCR: iQuant offer

Primer
design
(In silico)

Specificity testing

Primer
verification
(In silico)

If primers are provided

qPCR test development and optimization

Result analysis

Quantification or detection

Interpretation and reporting

Method transfer or delivery as a ready-to-use kit

Extraction ADN optimisée pour chaque matrice

selles, sols, peau, fermentés, etc.

Préparation des librairies

avec contrôles qualités intégrés

Séquençage haut-débit adapté

Analyse bioinformatique

Interprétation & Restitution

Primer
design
(in silico)

Specificity testing

Primer
verification
(in silico)

If primers are provided

qPCR test development and optimization

Result analysis

Quantification or detection

Interpretation and reporting

Method transfer or delivery as a ready-to-use kit

Pricing
Développement et optimisation du test qPCR

Adjustment of experimental conditions (temperature, concentrations, cycles)

Determination of LoD and LoQ

Inhibitor screening related to the analyzed matrix

Validation on real samples to ensure robustness and reproducibility

Interprétation et rendu

Clearly annotated report from our experts, including explanation of results and limitations

Optional oral presentation to ensure full understanding of outcomes

Transfert de méthode ou fourniture en kit prêt à l’emploi

We assist you in transferring the developed test onto your own qPCR platforms.
We also offer custom "ready-to-use" kit formulation for use in your labs or by your project partners.

Slide

Why choose GenoScreen?

GenoScreen - Scientific and regulatory expertise

Scientific and regulatory expertise

With a rigorous and transparent approach, we develop qPCR methods compliant with EFSA standards, particularly for residual DNA and GMM detection in finished products. Each step is validated under high-quality standards. Our methods are designed in compliance with ISO 9001 and can be adapted to GCLP and GMP requirements.

Accurate and actionable results

We provide complete reporting formats, including absolute or relative quantification and analytical validation according to your needs. Each project comes with detailed reports outlining development and optimization steps. We ensure regular interactions throughout the project with Go/No-Go decision checkpoints to guarantee optimal quality control and full transparency.

GenoScreen - Accurate and actionable results

Flexibility and personalized support

We design custom primers and probes (MGB, TaqMan, etc.) to ensure performance and specificity. Our client support is tailored, with regular communication, fast troubleshooting, and close monitoring at every stage. Our solutions are compatible with a wide variety of sample types: powders, liquids, environmental, or biological matrices.

Responsive and efficient service

Experience fast turnaround times (6 to 8 weeks) for qualitative or quantitative analyses, fully tailored to your needs. Receive personalized support with a dedicated contact for smooth follow-up from design to results interpretation.

Custom qPCR: key application areas

Our custom qPCR services are applicable across multiple sectors:

Human Health & Microbiota : Quantification of specific strains and gene-of-interest quantification

Agri-food Industry : Detection of residual DNA, validation of manufacturing processes, regulatory dossiers (e.g., EFSA) for genetically modified strains

Biotechnology : Monitoring of microbial cultures, quality control of finished products, rapid diagnostics for recurrent contaminants

Detection of residual DNA from genetically modified production strains in finished products

Detection of residual plasmid DNA after fermentation tank cleaning

Detection of target bacterial strains in environmental samples

Gene quantification under different culture conditions

Subcategories

At GenoScreen, our genomics expertise is built on collaboration with a dense network of scientific, industrial and institutional partners. These partnerships strengthen our ability to innovate, co-develop new technologies and advance research in molecular microbiology.

A network of strategic partners

We actively collaborate with:

Research institutes, universities and hospitals

 

 

Competitive clusters specialized in biotechnology and healthcare

 

Public funding bodies

 

A co-development strategy

Our research projects are carried out with recognized partners in France and abroad. Together, we can :

  • Co-develop innovative genomics and bioinformatics solutions
  • Reply to national and international applications for projects (Horizon Europe, ANR, etc.)
  • Test and validate our technologies in a variety of environments
  • Launch the implementation of concrete solutions for health, agriculture and the environment

 

Why collaborate with GenoScreen?

  • Access to an innovative sequencing technology platform
  • Access to recognized expertise in bioinformatics analysis and biomarkers
  • Benefit from our ability to manage collaborative R&D projects
  • Strive for health, agriculture and environment  

 

Join our network of partners

Do you represent a company, laboratory or public body? Contact us to discuss a collaboration or partnership.

 

 

Frequently asked questions

What kind of partners work with GenoScreen?

GenoScreen works with academic laboratories, biotech companies and clusters.

What are the benefits of these partnerships?

They help us co-develop technologies, co-finance projects and accelerate innovation.

How can I propose a partnership?

You can contact us via our contact form to discuss your project and identify a potential collaboration.

GenoScreen is a partner in collaborative research projects that bring together startups, multinationals and public-sector organizations. Our R&D teams provide their knowledge and expertise in the molecular microbiology of isolated agents and complex communities. This allowed our teams to develop our own projects for elaborating innovative products and services.

Our projects are designed to:

  • Improve the diagnosis and management of acute/chronic diseases on humans and animals,
  • Characterize and monitor microbial biodiversity, with applications in agronomy, agrifood and environment.

The common feature of these projects is the development of molecular tools for the characterization, monitoring and diagnosis of microbial communities. The key objective is to market simple analytical solutions and (ultimately) preventive, corrective or even therapeutic products based on microorganisms.

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