{"id":115,"date":"2017-12-16T15:25:31","date_gmt":"2017-12-16T14:25:31","guid":{"rendered":"https:\/\/www.genoscreen.fr\/caracterisation-et-tracage-des-microorganismes-isoles\/"},"modified":"2026-06-07T18:36:27","modified_gmt":"2026-06-07T16:36:27","slug":"caracterisation-et-tracage-des-microorganismes","status":"publish","type":"page","link":"https:\/\/www.genoscreen.fr\/fr\/genoscreen-expertise\/caracterisation-et-tracage-des-microorganismes\/","title":{"rendered":"Caract\u00e9risation et tra\u00e7age des microorganismes isol\u00e9s"},"content":{"rendered":"\n

A partir d\u2019un panel complet de technologies et de services en g\u00e9nomique<\/strong><\/a>, GenoScreen propose une vari\u00e9t\u00e9 de solutions d\u2019identification de microorganismes<\/strong> par s\u00e9quen\u00e7age d\u2019ADN<\/a> et de comparaison aux bases de donn\u00e9es internationales. Puissantes et pr\u00e9cises, ces solutions identifient et caract\u00e9risent tr\u00e8s pr\u00e9cis\u00e9ment les microorganismes<\/strong> d\u2019int\u00e9r\u00eat : identification \u00e0 l\u2019esp\u00e8ce, \u00e0 la sous-esp\u00e8ce ou \u00e0 la souche, typage, tra\u00e7age et antibior\u00e9sistance.<\/p>\n\n\n\n

L\u2019identification et la caract\u00e9risation<\/h2>\n\n\n\n

Pour une identification \u00e0 l’esp\u00e8ce, les r\u00e9gions de l\u2019ADN ribosomique<\/strong> interrog\u00e9es sont adapt\u00e9es \u00e0 chaque micro-organisme.<\/p>\n\n\n\n

En compl\u00e9ment, d\u2019autres cibles g\u00e9nomiques<\/strong> (g\u00e8nes rpoB, gyrB\u2026) sont utilis\u00e9es pour affiner l\u2019identification et l\u2019adapter \u00e0 votre demande (discrimination au sein d\u2019un groupe d\u2019esp\u00e8ces partageant la m\u00eame s\u00e9quence d\u2019ADN ribosomique, par exemple).<\/p>\n\n\n\n

GenoScreen peut aussi mobiliser ses savoir-faire en s\u00e9quen\u00e7age de g\u00e9nome complet (WGS)<\/a> pour une caract\u00e9risation plus pr\u00e9cise des souches : \u00e9valuation de la virulence et de la r\u00e9sistance aux antibiotiques<\/strong>, comparaisons g\u00e9nomiques<\/strong> sur le souchier\u2026<\/p>\n\n\n\n

Le typage et le tra\u00e7age microbien<\/h2>\n\n\n\n

Notre solution caract\u00e9rise pr\u00e9cis\u00e9ment tout microorganisme<\/strong> \u00e0 la sous-esp\u00e8ce ou \u00e0 la souche \u00e0 l\u2019aide de m\u00e9thodes mol\u00e9culaires<\/strong> standardis\u00e9es et valid\u00e9es de type MLST (MultiLocus Sequencing Typing) ou MLVA (Multiple Loci VNTR Analysis).<\/p>\n\n\n\n

Les sch\u00e9mas de typage publics sont utilis\u00e9s comme r\u00e9f\u00e9rence pour ces analyses (PubMLST, MLST.org et MicrobesGenotyping). L\u2019analyse peut aussi \u00eatre r\u00e9alis\u00e9e sur la base d\u2019un sch\u00e9ma de typage personnalis\u00e9.<\/p>\n\n\n\n

GenoScreen, leader mondial du g\u00e9notypage de la tuberculose<\/h2>\n\n\n\n

Gr\u00e2ce \u00e0 un savoir-faire technologique de pointe, GenoScreen est aujourd\u2019huile leader mondial pour le g\u00e9notypage<\/strong> et le tra\u00e7age<\/strong> des souches du complexe Mycobacterium tuberculosis<\/strong><\/em>, agent responsable de la tuberculose.<\/p>\n\n\n\n

La solution MIRU-VNTR<\/a> d\u00e9velopp\u00e9e par nos \u00e9quipes est utilis\u00e9e par de nombreux centres de soins et \u00e9quipes de recherche sous forme de kit ou de prestation de service. L\u2019approche compl\u00e9mentaire par spoligotypage est \u00e9galement possible, afin d’identifier des sous-esp\u00e8ces.<\/p>\n\n\n\n

Nous proposons des kits et des formations pour l’impl\u00e9mentation et l’usage optimis\u00e9 de la m\u00e9thode MIRU-VNTR sur s\u00e9quenceurs Applied Biosystems\u00ae<\/sup><\/a> et QIAGEN\u00ae<\/sup><\/a>, directement dans vos laboratoires hospitaliers ou de recherche.<\/p>\n\n\n\n

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En savoir plus<\/a><\/div>\n<\/div>\n\n\n\n

L’antibior\u00e9sistance<\/h2>\n\n\n\n

GenoScreen r\u00e9alise des antibiogrammes mol\u00e9culaires<\/strong> par s\u00e9quen\u00e7age cibl\u00e9 de g\u00e8nes connus<\/a> pour \u00eatre associ\u00e9s \u00e0 la r\u00e9sistance aux antibiotiques<\/strong> ou par s\u00e9quen\u00e7age de g\u00e9nome complet<\/strong>. Les s\u00e9quences sont compar\u00e9es aux banques de donn\u00e9es publiques accessibles ou aux informations disponibles dans la litt\u00e9rature.<\/p>\n\n\n\n

Le s\u00e9quen\u00e7age en profondeur NGS permet de d\u00e9tecter la pr\u00e9sence de variants minoritaires pouvant conf\u00e9rer la r\u00e9sistance (h\u00e9t\u00e9ror\u00e9sistance).<\/p>\n\n\n\n

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\"Identification<\/figure>\n<\/div>\n\n\n\n
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\"Identification<\/figure>\n<\/div>\n<\/div>\n\n\n\n

Deeplex\u00ae <\/sup>Myc-TB – La solution tout-en-un pour la caract\u00e9risation de Mycobacterium tuberculosis<\/em><\/h2>\n\n\n\n

La solution Deeplex\u00ae Myc-TB<\/a><\/strong> d\u00e9velopp\u00e9e par GenoScreen est une innovation majeure pour l\u2019identification, la caract\u00e9risation et la surveillance \u00e9pid\u00e9miologique de la tuberculose \u00e0 des fins de recherche.
Deeplex\u00ae Myc-TB<\/strong> constitue un test tout-en-un permettant l\u2019identification \u00e0 l\u2019esp\u00e8ce des mycobact\u00e9ries, le g\u00e9notypage<\/a> et la pr\u00e9diction de la r\u00e9sistance aux antibiotiques pour les souches du complexe Mycobacterium tuberculosis<\/em>.<\/p>\n\n\n\n

\n
En savoir plus<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

A partir d\u2019un panel complet de technologies et de services en g\u00e9nomique, GenoScreen propose une vari\u00e9t\u00e9 de solutions d\u2019identification de microorganismes par s\u00e9quen\u00e7age d\u2019ADN et de comparaison aux bases de donn\u00e9es internationales. Puissantes et pr\u00e9cises, ces solutions identifient et caract\u00e9risent tr\u00e8s pr\u00e9cis\u00e9ment les microorganismes d\u2019int\u00e9r\u00eat : identification \u00e0 l\u2019esp\u00e8ce, \u00e0 la sous-esp\u00e8ce ou \u00e0 la […]<\/p>\n","protected":false},"author":1,"featured_media":1050,"parent":2372,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"page-categories":[156],"class_list":["post-115","page","type-page","status-publish","has-post-thumbnail","hentry","page-categories-genoscreen-expertise"],"yoast_head":"\nCaract\u00e9risation et tra\u00e7age des microorganismes isol\u00e9s - GenoScreen<\/title>\n<meta name=\"description\" content=\"Genoscreen propose diverses solutions pour l'identification des micro-organismes par le s\u00e9quen\u00e7age de l'ADN et la comparaison avec des bases de donn\u00e9es internationales.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.genoscreen.fr\/fr\/genoscreen-expertise\/caracterisation-et-tracage-des-microorganismes\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Caract\u00e9risation et tra\u00e7age des microorganismes isol\u00e9s - 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