{"id":515,"date":"2020-11-17T10:55:23","date_gmt":"2020-11-17T09:55:23","guid":{"rendered":"https:\/\/www.genoscreen.fr\/microbial-signature-in-indoor-air-associated-evere-asthma\/"},"modified":"2026-06-07T15:44:34","modified_gmt":"2026-06-07T13:44:34","slug":"microbial-signature-in-indoor-air-associated-evere-asthma","status":"publish","type":"post","link":"https:\/\/www.genoscreen.fr\/en\/news\/microbial-signature-in-indoor-air-associated-evere-asthma\/","title":{"rendered":"A microbial signature in indoor air associated with severe asthma"},"content":{"rendered":"<p>Press release &#8211; Researchers from GenoScreen and the Cardio-Thoracic Research Centre of Bordeaux (Inserm U1045) have demonstrated relationships between microorganisms in indoor air and those in asthmatic patients\u2019 lungs. This work, published in the <em>Journal of Allergy and Clinical Immunology<\/em> and highlighted by the <a href=\"https:\/\/www.aaaai.org\/global\/latest-research-summaries\/Current-JACI-Research\/mycobiome\" target=\"_blank\" rel=\"noopener\">American Academy of Allergy, Asthma and Immunology (AAAI)<\/a>, also shows a variation in these micro- and mycobiota according to the patients\u2019 inflammatory reaction type (T2 endotype).<\/p>\n<p><!--more--><\/p>\n<p>Asthma is the most common chronic disease in children, although it can start at any age. It can be recognized by the recurrent episodes of breathing difficulties, called asthma attacks. Some acute attacks can last several hours or even days, conventional treatments not being able to calm them down. These episodes are called exacerbations.<br \/>The WHO estimates that currently 339 million people worldwide suffer from asthma. The deaths due to asthma are estimated to be more than 417,000 in 2016<sup>1<\/sup> , and WHO alerts on their increase in the next 10 years without public health measures<sup>2<\/sup> .<\/p>\n<p>Although the root causes of asthma are currently unknown, many risk factors have been identified, including bacteria and mildew of ambient air. The severity of asthma can also be reduced by limiting the exposure to the known triggers of its exacerbations (allergens, viruses, etc.).<\/p>\n<p>This pilot study published in the \u201c<em>Journal of Allergy and Clinical Immunology<\/em><sup>3<\/sup>\u201d is the first to highlight a relationship between the pulmonary bacterial and fungal communities of severe asthma patients and those of the indoor air in their homes. Carried out by the Cardio-Thoracic Research Center of Bordeaux (CRCTB, Inserm U1045, University of Bordeaux, Inserm, Bordeaux University Hospital) and GenoScreen (Lille), this study demonstrated a microbial signature in these microbial communities, specific to severe asthma, depending on the nature of the patients\u2019 inflammatory reaction. (Endotype T2.)<\/p>\n<p><a href=\"https:\/\/www.genoscreen.fr\/wp-content\/uploads\/presse\/CP_Kamyre_ENG_FINAL.pdf\" target=\"_blank\" class=\"wf_file\">Read more<\/a><\/p>\n<p><sup>1<\/sup>&nbsp;<a href=\"https:\/\/www.who.int\/fr\/news-room\/fact-sheets\/detail\/asthma\">https:\/\/www.who.int\/fr\/news-room\/fact-sheets\/detail\/asthma<\/a><br \/><sup>2<\/sup>&nbsp;<a href=\"https:\/\/www.who.int\/features\/factfiles\/asthma\/fr\/\">https:\/\/www.who.int\/features\/factfiles\/asthma\/fr\/<\/a><br \/><sup>3<\/sup>&nbsp;<a href=\"doi.org\/10.1016\/j.jaci.2020.08.035\" target=\"_blank\">doi.org\/10.1016\/j.jaci.2020.08.035<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Press release &#8211; Researchers from GenoScreen and the Cardio-Thoracic Research Centre of Bordeaux (Inserm U1045) have demonstrated relationships between microorganisms in indoor air and those in asthmatic patients\u2019 lungs. This work, published in the Journal of Allergy and Clinical Immunology and highlighted by the American Academy of Allergy, Asthma and Immunology (AAAI), also shows a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1212,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[167],"tags":[],"class_list":["post-515","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>A microbial signature in indoor air associated with severe asthma - GenoScreen<\/title>\n<meta name=\"description\" content=\"Researchers from GenoScreen and the Cardio-Thoracic Research Centre of Bordeaux (Inserm U1045) have demonstrated relationships between microorganisms in indoor air and those in asthmatic patients\u2019 lungs. This work, published in the Journal of Allergy and Clinical Immunology, also shows a variation in these micro- and mycobiota according to the patients\u2019 inflammatory reaction type (T2 endotype).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.genoscreen.fr\/en\/news\/microbial-signature-in-indoor-air-associated-evere-asthma\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A microbial signature in indoor air associated with severe asthma - GenoScreen\" \/>\n<meta property=\"og:description\" content=\"Researchers from GenoScreen and the Cardio-Thoracic Research Centre of Bordeaux (Inserm U1045) have demonstrated relationships between microorganisms in indoor air and those in asthmatic patients\u2019 lungs. This work, published in the Journal of Allergy and Clinical Immunology, also shows a variation in these micro- and mycobiota according to the patients\u2019 inflammatory reaction type (T2 endotype).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.genoscreen.fr\/en\/news\/microbial-signature-in-indoor-air-associated-evere-asthma\/\" \/>\n<meta property=\"og:site_name\" content=\"GenoScreen\" \/>\n<meta property=\"article:published_time\" content=\"2020-11-17T09:55:23+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-07T13:44:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.genoscreen.fr\/wp-content\/uploads\/news\/actu-asthme-site-ConvertImage.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1445\" \/>\n\t<meta property=\"og:image:height\" content=\"876\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Simon\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@genoscreen\" \/>\n<meta name=\"twitter:site\" content=\"@genoscreen\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Simon\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/news\\\/microbial-signature-in-indoor-air-associated-evere-asthma\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/news\\\/microbial-signature-in-indoor-air-associated-evere-asthma\\\/\"},\"author\":{\"name\":\"Simon\",\"@id\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/#\\\/schema\\\/person\\\/16f77d942ec357acc1c3aa8c53b1e71c\"},\"headline\":\"A microbial signature in indoor air associated with severe asthma\",\"datePublished\":\"2020-11-17T09:55:23+00:00\",\"dateModified\":\"2026-06-07T13:44:34+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/news\\\/microbial-signature-in-indoor-air-associated-evere-asthma\\\/\"},\"wordCount\":327,\"publisher\":{\"@id\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/news\\\/microbial-signature-in-indoor-air-associated-evere-asthma\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.genoscreen.fr\\\/wp-content\\\/uploads\\\/news\\\/actu-asthme-site-ConvertImage.jpg\",\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/news\\\/microbial-signature-in-indoor-air-associated-evere-asthma\\\/\",\"url\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/news\\\/microbial-signature-in-indoor-air-associated-evere-asthma\\\/\",\"name\":\"A microbial signature in indoor air associated with severe asthma - GenoScreen\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/news\\\/microbial-signature-in-indoor-air-associated-evere-asthma\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.genoscreen.fr\\\/en\\\/news\\\/microbial-signature-in-indoor-air-associated-evere-asthma\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.genoscreen.fr\\\/wp-content\\\/uploads\\\/news\\\/actu-asthme-site-ConvertImage.jpg\",\"datePublished\":\"2020-11-17T09:55:23+00:00\",\"dateModified\":\"2026-06-07T13:44:34+00:00\",\"description\":\"Researchers from GenoScreen and the Cardio-Thoracic Research Centre of Bordeaux (Inserm U1045) have demonstrated relationships between microorganisms in indoor air and those in asthmatic patients\u2019 lungs. 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