{"id":197,"date":"2017-12-16T15:25:31","date_gmt":"2017-12-16T14:25:31","guid":{"rendered":"https:\/\/www.genoscreen.fr\/characterization-and-tracking-isolated-microorganisms\/"},"modified":"2026-06-07T18:38:46","modified_gmt":"2026-06-07T16:38:46","slug":"characterization-and-tracking-isolated-microorganisms","status":"publish","type":"page","link":"https:\/\/www.genoscreen.fr\/en\/genoscreen-expertise\/characterization-and-tracking-isolated-microorganisms\/","title":{"rendered":"Characterization and tracking of isolated microorganisms"},"content":{"rendered":"\n

By applying a broad panel of genomic technologies and services<\/a>, GenoScreen provides various solutions in identifying microorganisms <\/strong>via DNA sequencing<\/a> and comparison with international databases.These powerful and precised solutions are able to identify and characterize the microorganisms of interest: the species, the sub-species or the strain, typing, tracking and antibiotic resistance. <\/p>\n\n

Identification and characterization<\/h2>\n\n

In order to identify a specie, ribosomal DNA<\/strong> regions targeted are adapted to each microorganism.<\/p>\n\n

Additionally, to refine and adapt the identification to your needs, other genomic targets<\/strong> (rpoB and gyrB genes, etc.) are then used (discrimination within a group of species sharing the same ribosomal DNA sequence, for example).<\/p>\n\n

GenoScreen can also leverage its know-how in whole-genome sequencing<\/a> for a more precised characterization of a strain : virulence, antibiotic resistance<\/strong>, genomic <\/strong>comparisons with the strain library, etc.<\/p>\n\n

Microbial typing and tracking<\/h2>\n\n

Our solution precisely characterizes any microorganism <\/strong>at the sub-species or strain level by using standardized, validated molecular methods<\/strong>, such as multilocus sequence typing (MLST) and multiple loci VNTR analysis (MLVA).<\/p>\n\n

The typing schemes in open-access databases (PubMLST, MLST.org and MicrobesGenotyping) are used as references for these analyses.The analysis can also be performed on a custom typing scheme. <\/p>\n\n

GenoScreen, the world leader in tuberculosis genotyping<\/h2>\n\n

Credits to its cutting-edge technological know-how, GenoScreen is now the leader worldwide in genotyping <\/strong>and tracking of the Mycobacterium tuberculosis<\/strong><\/em> complex strains (the agent that causes tuberculosis).<\/p>\n\n

The MIRU-VNTR<\/a> solution developed by our teams is used as a kit or a service by many healthcare centers and research groups. A complementary spoligotyping approach is also available for identifying sub-species. <\/p>\n\n

We propose kits and training courses for the implementation and an optimized use of the MIRU-VNTR method on Applied Biosystems\u00ae<\/sup><\/a> and QIAGEN\u00ae<\/a> sequencers in your hospital or lab.<\/p>\n\n

\n
Learn more<\/a><\/div>\n<\/div>\n\n

Antibiotic resistance<\/h2>\n\n

GenoScreen determines antibiotic resistance<\/strong> profiles via targeted sequencing of genes<\/a> known to be associated with antibiotic resistance or by whole-genome sequencing<\/strong>. The sequences are compared with open-access databases or the literature data. <\/p>\n\n

In-depth NGS sequencing can detect the presence of low-frequency variants conferring resistance (heteroresistance).<\/p>\n\n

\n
\n
\"Identification<\/figure>\n<\/div>\n\n\n\n
\n
\"Identification<\/figure>\n<\/div>\n<\/div>\n\n

Deeplex\u00ae<\/sup>-MycTB – The all-in-one solution for characterizing Mycobacterium tuberculosis<\/em><\/h2>\n\n

La solution Deeplex\u00ae Myc-TB<\/a><\/strong> d\u00e9velopp\u00e9e par GenoScreen est une innovation majeure pour l\u2019identification, la caract\u00e9risation et la surveillance \u00e9pid\u00e9miologique de la tuberculose \u00e0 des fins de recherche. Deeplex\u00ae Myc-TB<\/strong> constitue un test tout-en-un permettant l\u2019identification \u00e0 l\u2019esp\u00e8ce des mycobact\u00e9ries, le g\u00e9notypage<\/a> et la pr\u00e9diction de la r\u00e9sistance aux antibiotiques pour les souches du complexe Mycobacterium tuberculosis<\/em>.<\/p>\n\n

\n
Learn more<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

By applying a broad panel of genomic technologies and services<\/strong><\/a>, Genoscreen provides various solutions in identifying microorganisms<\/strong> via DNA sequencing<\/strong> and comparison with international databases.
These powerful and precised solutions are able to identify and characterize the microorganisms<\/strong> of interest: the species, the sub-species or the strain, typing, tracking and antibiotic resistance.<\/p>\n

Identification and characterization<\/h2>\n

In order to identify a specie, ribosomal DNA regions targeted are adapted to each microorganism<\/strong>.<\/p>\n

Additionally, to refine and adapt the identification to your needs, other genomic targets (rpoB and gyrB genes, etc.) are then used (discrimination within a group of species sharing the same ribosomal DNA sequence, for example).<\/p>\n

Genoscreen can also leverage its know-how in whole-genome sequencing<\/a> for a more precised characterization<\/strong> of a strain : virulence, antibiotic resistance, genomic comparisons with the strain library, etc.<\/p>\n

Microbial typing and tracking<\/h2>\n

Our solution precisely characterizes any microorganism at the sub-species or strain level by using standardized, validated molecular methods<\/strong>, such as multilocus sequence typing (MLST) and multiple loci VNTR analysis (MLVA).<\/p>\n

The typing schemes in open-access databases (PubMLST, MLST.org and MicrobesGenotyping) are used as references for these analyses.
The analysis can also be performed on a custom typing scheme.<\/p>\n

 <\/p>\n

\n
\n

Genoscreen, the world leader in tuberculosis genotyping<\/h2>\n<\/div>\n
\n

\"Genoscreen,<\/p>\n

Credits to its cutting-edge technological know-how, Genoscreen is now the leader worldwide in genotyping and tracking of the Mycobacterium tuberculosis<\/em> complex strains (the agent that causes tuberculosis).<\/p>\n

The MIRU-VNTR<\/a> solution developed by our teams is used as a kit or a service by many healthcare centers and research groups<\/strong>. A complementary spoligotyping approach is also available for identifying sub-species. <\/p>\n

We propose kits and training courses for the implementation and an optimized use of the MIRU-VNTR method on Applied Biosystems\u00ae and QIAGEN\u00ae sequencers in your hospital or lab.<\/p>\n

For more information<\/a><\/p>\n<\/div>\n<\/div>\n

 <\/p>\n

Antibiotic resistance<\/h2>\n

Genoscreen determines antibiotic resistance<\/strong> profiles via targeted sequencing of genes known to be associated with antibiotic resistance or by whole-genome sequencing. The sequences are compared with open-access databases or the literature data.<\/p>\n

In-depth NGS sequencing<\/a> can detect the presence of low-frequency variants conferring resistance (heteroresistance).<\/p>\n

\n
\"Genoscreen,<\/div>\n
\"Genoscreen,<\/div>\n<\/div>\n
\n
\n

Deeplex\u00ae<\/sup>-MycTB – The all-in-one solution for characterizing Mycobacterium tuberculosis<\/h2>\n<\/div>\n
\n

The Deeplex\u00ae<\/sup>-MycTB solution<\/a> developed by Genoscreen is a major innovation for the identification, characterization and epidemiological surveillance of tuberculosis for research purposes.
Deeplex\u00ae<\/sup>-MycTB<\/strong> is an all-in-one test for species-level identification, genotyping and prediction of antibiotic resistance in Mycobacterium tuberculosis<\/em> complex strains.<\/p>\n

For more information<\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"author":1,"featured_media":1088,"parent":2374,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"page-categories":[159],"class_list":["post-197","page","type-page","status-publish","has-post-thumbnail","hentry","page-categories-genoscreen-expertise"],"yoast_head":"\nCharacterization and tracking of isolated microorganisms - GenoScreen<\/title>\n<meta name=\"description\" content=\"Genoscreen provides various solutions in identifying microorganisms via DNA sequencing and comparison with international databases.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.genoscreen.fr\/en\/genoscreen-expertise\/characterization-and-tracking-isolated-microorganisms\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Characterization and tracking of isolated microorganisms - 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