{"id":193,"date":"2016-05-30T16:33:24","date_gmt":"2016-05-30T14:33:24","guid":{"rendered":"https:\/\/www.genoscreen.fr\/differential-gene-expression-understanding-the-impact-of-genes-on-cell-behavior\/"},"modified":"2026-06-07T17:57:40","modified_gmt":"2026-06-07T15:57:40","slug":"differential-gene-expression","status":"publish","type":"page","link":"https:\/\/www.genoscreen.fr\/en\/genomic-services\/differential-gene-expression\/","title":{"rendered":"Differential gene expression &#8211; Understanding the impact of genes on cell behavior"},"content":{"rendered":"\n<p class=\"intro wp-block-paragraph\"><strong>Gene expression<\/strong> is a major field of investigation with the goal of a better understanding of the mechanisms of action that underlie a <strong>cell\u2019s behavior<\/strong>. Genoscreen offers a comprehensive range of differential genomics analyses, so that you can identify biomarkers of interest.<\/p>\n\n<h2 class=\"wp-block-heading\">Applications of differencial genomics<\/h2>\n\n<p class=\"wp-block-paragraph\"><strong>RNA-Seq<\/strong> technologies provide the <strong>differential expression<\/strong> analysis of an entire <strong>genome <\/strong>in an organism and the comparison of the level of <strong>gene expression<\/strong> between two conditions, for the research of <strong>biomarkers <\/strong>of interest :<\/p>\n\n<ul class=\"wp-block-list\">\n<li>Comparisons of healthy and diseased tissues.<\/li>\n\n\n\n<li>Comparisons of <strong>cell behavior<\/strong> in two different environments (as a function of nutrition, stress, pollution, etc.)<\/li>\n\n\n\n<li>Comparisons of <strong>cell behavior<\/strong> at different stages of biological development.<\/li>\n<\/ul>\n\n<p class=\"wp-block-paragraph\">This exhaustive approach has several advantages:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>No requirement for prior knowledge of the organism being studied.<\/li>\n\n\n\n<li><strong>Whole-transcriptome<\/strong> analysis, <em>hypothesis-free<\/em> on the genes of interest<\/li>\n\n\n\n<li>The ability to use <strong>sequencing <\/strong>data to generate a <strong><a href=\"https:\/\/www.genoscreen.fr\/en\/genomic-services\/sequencing\/next-generation-sequencing-ngs\/transcriptomics\/\" type=\"page\" id=\"56\">transcriptome<\/a> <\/strong><em>de novo<\/em>.<\/li>\n\n\n\n<li>Analysis of natural antisense transcripts (NATs).<\/li>\n<\/ul>\n\n<h2 class=\"wp-block-heading\">GenoScreen &#8211; Differencial genomics services provided<\/h2>\n\n<p class=\"wp-block-paragraph\">Our teams offer comprehensive and personalized support:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>Assistance with study design<\/li>\n\n\n\n<li><strong>RNA purification<\/strong><\/li>\n\n\n\n<li>Library preparation and sequencing<\/li>\n\n\n\n<li>Pooling and sequencing<\/li>\n\n\n\n<li><a href=\"https:\/\/www.genoscreen.fr\/en\/genomic-services\/bioinformatics\/\" type=\"page\" id=\"112\">Bioinformatics<\/a> analysis<\/li>\n<\/ul>\n\n<h2 class=\"wp-block-heading\">GenoScreen&#8217;s assets<\/h2>\n\n<ul class=\"wp-block-list\">\n<li>Full-service provision <strong>from study design to bioinformatics analysis<\/strong> of the results.<\/li>\n\n\n\n<li>Optimized protocols for maximizing <strong>sensitivity<\/strong>, reliability, and <strong>reproducibility<\/strong>.<\/li>\n\n\n\n<li>Precise summary reports, detailing the most significant differences.<\/li>\n<\/ul>\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-04478499 wp-block-buttons-is-layout-flex\" style=\"margin-top:20px;margin-bottom:20px\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-elementor-28-fc-130-color has-elementor-primary-background-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.genoscreen.fr\/en\/genomic-services\/request-a-quote-genomic-analysis\" style=\"border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-left-radius:0px;border-bottom-right-radius:0px\">Request a quote<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Gene expression is a major field of investigation with the goal of a better understanding of the mechanisms of action that underlie a cell\u2019s behavior. Genoscreen offers a comprehensive range of differential genomics analyses, so that you can identify biomarkers of interest. Applications of differencial genomics RNA-Seq technologies provide the differential expression analysis of an [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2361,"parent":2225,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"page-categories":[158],"class_list":["post-193","page","type-page","status-publish","has-post-thumbnail","hentry","page-categories-genoscreen-services"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Differential gene expression - Understanding the impact of genes on cell behavior - GenoScreen<\/title>\n<meta name=\"description\" content=\"Genoscreen offers a comprehensive range of differential genomics analyses, so that you can identify biomarkers of interest.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.genoscreen.fr\/en\/genomic-services\/differential-gene-expression\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Differential gene expression - 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