Skin Care

Genomics, and above all metagenomics, constitute the sharpest method for studying interaction between skin and its microbiota, and analysis the entirety of the microorganism communities present on the epidermis.

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Our analytical solutions for dermocosmetics

GenoScreen, scientific partner for the beauty and skincare sector

Microbiote de la peau

GenoBiome®

Notre offre intégrale pour l’analyse des communautés de microorganismes de la peau

Analyse du microbiome cutané

Cosmétique « microbiome friendly » attestant de l’innocuité d’un produit sur la flore cutanée

Métagénomique

Métagénomique ciblée 16S (bactéries), 18S/ITS (fongiques) en short read et long read, métagénomique shotgun à partir d’écouvillonnages cutanés (swabs)

Expertise & savoir-faire

Bioinformatique

Pipelines développés par GenoScreen spécifiques au microbiote cutané, rapports de bioinformatique interactifs au contenu clair et accessible

Conformité réglementaire

Preuves scientifiques d’allégations cosmétiques pour répondre aux exigences de la réglementation

Redefine Service

Accompagnement de la conception du protocole expérimental à la restitution des résultats et à leur interprétation, notre équipe de microbiologistes s’attachent à fournir des réponses précises à vos questions biologiques

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Examples of GenoScreen’s involvement in various R&D projects in the field of dermocosmetics

Slide 1

Microbiome Modulation in Acne Patients and Clinical Correlations

https://doi.org/10.3390/life14060688

Ionescu M-A, Tatu AL, Busila C, Axente ER, Badalato N, Feuilloley MGJ, Asquier E, Martínez JD, Lefeuvre L. Microbiome Modulation in Acne Patients and Clinical Correlations. Life. 2024; 14(6):688.

Slide 2

Respect of Skin Microbiome with Different Types of LeavE-on Skincare Products, an Ecobiological Approach

https://doi.org/10.20944/preprints202005.0500.v1

Callejon, S., Giraud, F., Larue, F., Buisson, A., Matéos, L., Grare, L., Guyoux, A., Perrier, E., Ardiet, N., & Trompezinski, S. (2020). Respect of Skin Microbiome with Different Types of LeavE-on Skincare Products, an Ecobiological Approach. Preprints.

Slide 3

Effects of a New Emollient-Based Treatment on Skin Microflora Balance and Barrier Function in Children with Mild Atopic Dermatitis

https://doi.org/10.1111/pde.12786

Bianchi, P., Theunis, J., Casas, C., Villeneuve, C., Patrizi, A., Phulpin, C., Bacquey, A., Redoulès, D., Mengeaud, V., & Schmitt, A. M. (2016). Effects of a New Emollient-Based Treatment on Skin Microflora Balance and Barrier Function in Children with Mild Atopic Dermatitis. Pediatric dermatology, 33(2), 165–171.

Slide 4

Complete Genome Sequence of Staphylococcus epidermidis PH1-28, Isolated from the Forehead of a Hyperseborrheic Donor

https://doi.org/10.1128/MRA.00165-21

Hilaire, P., Landemaine, L., Contreras, S., Blanquart-Goudezeune, H., Siguier, P., Cornet, F., Chiapello, H., Loux, V., Clavaud, C., & Morand, S. C. (2021). Complete Genome Sequence of Staphylococcus epidermidis PH1-28, Isolated from the Forehead of a Hyperseborrheic Donor. Microbiology resource announcements, 10(9), e00165-21.

Slide 5

Staphylococcus epidermidis isolates from atopic or healthy skin have opposite effect on skin cells: potential implication of the AHR pathway modulation

https://doi.org/10.3389/fimmu.2023.1098160

Landemaine, L., Da Costa, G., Fissier, E., Francis, C., Morand, S., Verbeke, J., Michel, M. L., Briandet, R., Sokol, H., Gueniche, A., Bernard, D., Chatel, J. M., Aguilar, L., Langella, P., Clavaud, C., & Richard, M. L. (2023). Staphylococcus epidermidis isolates from atopic or healthy skin have opposite effect on skin cells: potential implication of the AHR pathway modulation. Frontiers in immunology, 14, 1098160.